Oral EDTA Removes Lead From The Body
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There seems to be no question that EDTA, taken intravenously, is effective in removing metals from the body. However, it is interesting to consider whether or not ORAL EDTA also removes metals from the body.
In
the early years EDTA was sold in "pill" form
and was then listed in the Physician's Desk
Reference. It was then accepted as the
standard method of ridding the body of lead.
This was actually BEFORE the time when EDTA
became used for IV chelation therapy.
It was common in that period of time for ship yards where workers were exposed to large amounts of lead in the paint they were using -- common for them to get excessive lead into their symptoms and come down with the symptoms of lead poisoning. The "cure" then was simple. The ship yard office would simply keep bottles of EDTA capsules and give the men a few capsules to clear up the symptoms, to remove the lead from the system.
There were studies of the effectiveness of oral EDTA during this time, but they were so far back in time that they are earlier than the usual electronic forms of scientific studies -- published around 1960 and earlier. Thus, these studies have not been available for the "electronic public" and that entire technology is virtually lost in the form of scientific validation.
The EDTA capsules, in the Physician's Desk Reference, concerned the Government that felt that lead paint was such a health hazard that they didn't want workers to be exposed to it -- even if some capsule might reverse the symptoms.
Regarding the dosage of oral EDTA, the average recommended daily adult dose for asymptomatic lead toxicity was 4gm in divided doses; and for children, it was 1gm daily per 35 lbs of body weight in divided doses. The PDR states that the drug is approximately 5% to 10% absorbed in man. It states that with the increased excretion of lead in the urine there is a concomitant decrease in blood lead levels. Earlier editions of the PDR stated that EDETATE can dissolve ordinarily insoluble salts such as barium sulfate and lead phosphate in the neutral and alkaline pH ranges. This solubilizing property accounts for the value of this agent as a means for mobilizing heavy metal from the body.
(Physicians’ Desk Reference, 30th Ed. 1976, Riker, p1248. Copyright© by Litton Industries, Inc., Published by Medical Economics Company, a Litton division, at Oradell, NJ 07649.) (source)
So, the story goes, the Government "leaned" on the publishers of the Physician's Desk Reference to REMOVE the reference to oral EDTA usage, and around that time intravenous chelation started being used. Of course IV chelation could only be done by doctors.
This story became the backdrop to a disagreement between Dr. Gary F. Gordon, one of the founders of the American College of Advancement In Medicine (as it is now known) and the Board of Directors of that group. Dr. Gordon was so convinced that oral EDTA would be effective that he wanted to present evidence he had about that to the membership of his own group -- ACAM. The Board, by that time, felt strongly that oral EDTA would destructively competitive to their membership and had adopted a firm policy of claiming that oral EDTA was worthless as a remedy.
As brilliant as Dr. Elmer Cranton seems to be, on the technology of IV chelation, he has become one of the most vocal of the critics of oral EDTA. His comments on oral EDTA are HERE. Dr. Cranton, on that page, says:
It is deceptive, irresponsible and perhaps even dangerous to promote EDTA (ethylene diamine tetraacetic acid) by mouth as so-called “oral chelation”. While intravenous EDTA chelation is a safe, effective and inexpensive treatment for coronary heart disease, atherosclerosis and other age-related diseases, there’s no reliable evidence that the same is true for EDTA by mouth. And there’s good reason to believe that it’s potentially harmful. (source)
Dr. Gary Gordon continued his campaign to get the Board of ACAM to allow him to present his evidence, and was rejected.
He finally quit from ACAM over this issue. He had, at one time, the second largest practice in IV chelation in the world -- second only to Dr. Robert Atkins. Dr. Gordon continues to be one of the most knowledgeable sources of information about chelation therapy, and has now introduced his own formula of "oral chelation" using oral EDTA. In fact my own formula for oral chelation had been developed years before, based on Cysteine. At that time I accepted the claims made by Dr. Cranton and I was very vocal in also criticizing oral EDTA usage. Then Dr. Gordon posted onto his web site a large number of studies, and his own opinion, that oral chelation was a valid therapy, based on use of oral EDTA (as well as Cysteine and N AcetylCysteine -- NAC).
The story about Dr. Gordon's disagreements with ACAM is HERE.
Here is an excerpt from this page, part of one of the letters written by Dr. Gordon to someone in ACAM:
"The effect of various ligands on the absorption, distribution, and excretion of iron following oral administration." W. Forth, et al, Arch. Exptl. Pathol. Pharmakol. 252(3), 242-57 (1965) (Ger.) In the presence of EDTA, diminished iron retention appeared to be due to a marked increase in excretion. Furthermore, EDTA-bound iron is poorly utilized by the erythropoietic system.
"Food iron absorption in man; the effect of EDTA on absorption of dietary non-heme iron." Amer. J. of Clin. Nut. 1976: 29(6), 614-620. This study reports a decrease of absorption of non-heme iron of 72% when EDTA is present at a 2:1 molar ratio.
"Effect of orally administered EDTA on iron absorption in man." P. S. Davis et al. Australis Ann. Med. 16(1), 70-4. 1967. EDTA significantly reduces iron absorption when present in a ratio of 10:1 or more.
"The Enhancement of Iron Excretion in Iron-Storage Diseases," W.G. Figueroa. Metal-Binding in Medicine, M.J. Seven, M.D., ed., J.B. Lippincot, Ch. 17 (1960). This study claims that oral EDTA does not increase output of iron in the urine.
"The Effect of the Prolonged Intake of EDTA on the Utilization of Calcium & Iron by the Rat." B.A. Larsen, Can. J. Biochem. Physiol. Vol. 38 (1960) p. 813-817. This author states that EDTA ingestion causes less iron to be absorbed, and more of what is absorbed to be excreted.
"Effect of pH and chelating agents on iron binding by dietary fiber: implications for iron availability." M.J. Leigh, Am J Clinical Nutrition 38: Aug 1983, p 202-213. This article states that all iron research must take into account the level of ascorbic acid. The key end result may be assumed to be due to the great stability of the iron/EDTA complex at all pH levels.
"A comparison of the effect of Fe-3-Specific EDTA on urinary iron excretion in a patient with hemochromatosis." F. Gilbert McMahon, Journal of Lab and Clinical Med., p. 600, October 1956. This reports a two-fold increase in urinary iron excretion from intravenous administration.
"Design of chelates for therapeutic objectives." Martin Rubin, Fed Proc 20(Suppl.10; Pt.2):149-157. Sept 1961, states that EDTA is able to hold iron in the presence of even a specific iron-binding protein (siderophilin) of the plasma. Dr. Rubin states that iron, presented to the cell in the form of an EDTA chelate, is unavailable for incorporation into hemoglobin. This strongly suggests that it is not available to catalyze free radical pathology!
I believe that your concern that oral EDTA might chelate out normal minerals through the GI tract has been more than adequately answered by the 21 abstracts and/or portions of published articles I am submitting that show in fact oral EDTA appears to treat malabsorption problems, and that EDTA is apparently absorbed as the complexes of several minerals (Exhibit 2). In fact there are two rat studies (Exhibit 2) that indicate increased deposition of calcium and phosphorus in the bones following oral EDTA administration. (See Abstracts No. CA55:5762e, Vozar; CA54:25290h, Vozar, both included.) EDTA has been able to virtually substitute for zinc in zinc-deficient animals, and has been shown to enhance the absorption of heparin, Vit. B12, and increase the blood levels of antibiotics in chickens by 100%. Special salts of iron EDTA are being considered for worldwide application because of these well documented studies on EDTA, which is commonly used as a feed additive for animals and thus has been studied extensively.
I agree with you that the effective dose of EDTA in products ought to be at least 500 mg, preferably 800 or more. Researchers calculate the average human is already ingesting 15 to 50 mg in their standard diet.
Your comment that "There is evidence that lead workers taking oral EDTA can reduce the amount absorbed into the body" clearly indicates that ACAM failed to provide you with any of the 88 abstracts and portions of 27 published articles that I am supplying to you at this time (Exhibit 4), which is but a fraction of what Mr. Scharffenberg has collected. These references come from mainstream medicine, and have documented without exception an increase of excretion of lead with oral EDTA of from 3 to 30 times. Virtually every one of these articles describes significant lead lowering benefits from the oral ingestion of EDTA.
Dr/ Gordon has carried this fight to various doctors within ACAM and other IV chelation doctors. CLICK HERE for another document describing the effectiveness of oral EDTA.
I have another detailed reference to the effectiveness of oral EDTA HERE.
The above are just some of the references to oral EDTA on ONE of my web sites. Here is a more complete "clickable" list.
ACAM Revealed as Suppressing Evidence about oral
EDTA
... Link To More Than 500
Pages About EDTA, Particularly Oral
EDTA. ... If was from
these fine doctors that I first learned that "oral
EDTA is useless.". ...
www.oralchelation.net/data/Dr_Garry_F_Gordon/
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THE GREAT ORAL EDTA CHELATION DEBATE
... THE GREAT ORAL
EDTA CHELATION DEBATE. ... Several other
cases of marked
beneficial results with oral EDTA are
reported in this article. ...
www.oralchelation.net/data/EDTA/data14ao.htm
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Oral EDTA data
... ORAL EDTA --
The Family Friend. Life Flow One The ... heart
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were treated with 1 gm of oral EDTA
daily for 3 months. Seven of ...
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Dr Garry F Gordon. Advocate Of
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of Oral EDTA Chelation. This is the web
site where lies are ...
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Oral EDTA, Lead & More
... Oral EDTA,
Lead & More. Life Flow One ... Chapter 17
(1960). This study claims
that oral EDTA does not increase output
of iron in the urine. ...
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Longevity Expert Garry F. Gordon, MD, advocate of
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Dr Garry F Gordon. Longevity Expert
Dr. Garry F. Gordon -- Advocate
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site where lies are exposed ...
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Cranton
... Oral EDTA --
An Opinion Life Flow One The Solution For Heart
Disease.
by Karl Loren. MOUNT ROGERS CLINIC Trout Dale,
Virginia MOUNT ...
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Advocating Oral ...
... About Oral
Chelation, ...2... An astonishing set of public
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the benefits of oral EDTA. ...
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any of the following topics: ...
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formula or any of the following topics: ...
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... Gordon. Life Flow One
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by Karl Loren. Oral EDTA, Lead &
More. ... lead... ...
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... is published. Karl Loren
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...
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... 3.) Benefits of oral
EDTA on cholesterol metabolism. 4.) 115
references showing
positive benefits with oral EDTA in
lead toxicity. 5.) HH Dieter. ...
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EDTA
... 18... EDTA For
Intravenous & Oral Chelation, ...19...
... 23... Chelation Oral
EDTA - A Food Additive with Many Remarkable
Properties. ...24... ...
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... ORAL CALCIUM
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Journal of Pediatrtics Volume
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IN LEAD INTOXICATION OF CHILDREN. ...
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Chelation, Toxic Metals, Free Radicals and Heart
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... I/V Chelation uses "EDTA"
and you will get amazing inside information on
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oral chelation
... Oral EDTA,
which does not require a physician's intervention,
is probably
even safer. ... After oral EDTA,
their black feet became pink again.". ...
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Toxic Lead And EDTA
... Results for your query
on March 15, 1999: Search all fields for: lead And
oral
EDTA Published in 1966 through 1999 Only
select references with abstracts ...
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EDTA References
... (16) Gordon GF: Oral
chelation with EDTA. J Holistic Medicine,
8(1):79-80,
1986. ... Oral EDTA, a
bibliography, Vitamin Research Products, Inc.
...
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Comments on New Revelations by Karl Loren
... When I referred you to
the articles on EDTA, I did so tentatively.
I have read
at length how you felt (before) about those who
tout EDTA in oral form. ...
www.oralchelation.net/karl/NewRevelation/data3c.htm
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... EDTA -- CALCIUM
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5 to 10% of oral calcium disodium edetate is
absorbed in man. ...
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Table Of Contents
... Heart Disease. ...
published. Karl Loren is the author and webmaster
for this
BOOK, as well as for another web site about ORAL
CHELATION. He ...
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On Heart ...
... In fact, on his web site
he has a full explanation of his position on the
use
of oral EDTA for chelating purposes.
Click here to read that statement. ...
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... ..10... Toxic Lead
Scientific Studies, ...11... Toxic Lead & Oral
EDTA 26
Studies, ...12... Toxic Lead Levels, 50 Studies.
...13... ..14... ..15... ...
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EDTA For Sale
... EDTA Chelation is
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as for another web site about ORAL ...
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... EDTA Data. Life
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web site about ORAL ...
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EDTA Function -- An Article
... drastic procedures for
illnesses which could have been prevented with
oral chelation,
and many even most of which can still be treated
successfully with EDTA. ...
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CHELATION THERAPY IN LEAD NEPHROPATHY
... In man, however, Bell et
al 12 and Shiels et al 13 have demonstrated
increased
fecal lead content after oral EDTA
therapy, suggesting that fecal as well as ...
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Other EDTA References
... Halstead B Rozema T: The
Scientific basis of EDTA chelation therapy,
Landrum, SC ... M:
The miracle healing power of chelation therapy—the
intravenous and oral ...
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Longevity -- The Future Of Medicine -- Meet Garry F.
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... his current activities.
Dr. Gordon has amassed more technical information
on the use of oral EDTA than any other
single person. ...
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... EDTA And The
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webmaster for this BOOK, as well as for another web
site about ORAL ...
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Letter To Dr. Terry Chappell
... In your FAX you stated
that in the stack of documents you reviewed on
oral EDTA
there was very little evidence that it impacts
vascular disease improves ...
www.oralchelation.net/data/EDTA/data14am.htm
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Effect of Oral Edathamil Calcium-Disodium on
Urinary and Fecal ...
... Effect of Oral
Edathamil Calcium-Disodium on Urinary and Fecal Lead
Excretion.
Life Flow One The Solution For Heart Disease. by Karl
Loren. ...
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THE METABOLISM OF C14 LABELED ETHYLENEDIAMINETETRA-ACETIC
ACID IN ...
... For oral
administration, 1.5mg of C 14 labeled Ca EDTA
yielding approximately
1.6 x 10 7 d/m was dissolved in one-half ml. Of water
...
www.oralchelation.net/data/EDTA/data14q.htm
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Influence of Chelating Agents on the Gastrointestinal
Absorption
... lead (<0.001). The amount
of lead retained in the body after oral
Pb-EDTA was not significantly affected. The
urinary excretion ...
www.oralchelation.net/data/EDTA/data14y.htm
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GASTRO-INTESTINAL ABSORPTION OF HEPARIN AND SYNTHETIC
HEPARINOIDS
... after Oral
Sulphopolyglucin Plus EDTA. ... Table
2. Lipemia-Clearing Activity
and Clotting Time After oral Heparin Plus
EDTA in Rats and Dogs ...
www.oralchelation.net/data/EDTA/data14t.htm
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EFFECTS OF CALCIUM SODIUM ETHYLENEDIAMINETETRA-ACETATE
ON THE ...
... Finally, it has been
supposed that the oral use of EDTA
could increase
the intestinal absorption of lead. The increase in
urinary ...
www.oralchelation.net/data/EDTA/data14ah.htm
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International College of Advanced Longevity Medicine
... field. Back to the top.
... published. Karl Loren is the author and
webmaster
for this BOOK, as well as for another web site about
ORAL CHELATION. ...
www.oralchelation.net/data/Dr_Garry_F_Gordon/
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Chronic Lead Poisoning
... excess lead accumulation.
The ineffectiveness of the oral application
of CaNa 2 EDTA has been explained and
emphasized. It is true ...
www.oralchelation.net/data/EDTA/data14ai.htm
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EDTA
... alendronate. ...25...
Effects of smoking on the urine excretion of oral
51Cr EDTA in ulcerative colitis. ...26...
Ultrasonic subgingival ...
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Disodium
... AMA ARCH INDUST HEALTH v.
17, 1958. Oral Administration of Edathamil
Calcium Disodium. ... The
use of edathamil (Versene or EDTA) in the
treatment of lead poisoning ...
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References
... Ca-EDTA has a low
toxicity, and cysteine and acetylcysteine have even
lower toxicity. ... and
webmaster for this BOOK, as well as for another web
site about ORAL ...
www.oralchelation.net/karl/NewRevelation/data3b.htm
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OUR EXPERIENCES WITH CaNa2EDTA
... with CaNa 2 EDTA in
five cases of subacute mercury poisoning, which
allowed us to
estimate the efficiency of this therapeutic method.
[_private/navbarbook.htm] ...
www.oralchelation.net/data/EDTA/data14ab.htm
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Treatment of Lead poisoning by Edathamil
Calcium-Disodium
... fourth day. These
investigators found five to ten-fold increases in
urinary excretion of lead follow oral
administration of EDTA. ...
www.oralchelation.net/data/EDTA/data14o.htm
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EDTA
... EDTA Data. Life
Flow One The Solution For Heart Disease. by Karl
Loren. Top ... 197-211.
12 Id, at pp. 107-226. Degradation Of Vitamin C ==
relative to EDTA. ...
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Medicine's Modern ...
... I learned about oral
chelation by the use of [Vibrant Life] vitamins.
... thousands
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because a substance (EDTA ...
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agents to
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...
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Data
Section
... We reverse. ...21...
EDTA, ...22... Intravenous Chelation Therapy,
...23... Dr.
Garry F. Gordon Foremost Medical Doctor Advocate Of
Oral Chelation, ...24... ...
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Pran Vohra and FH Kratzer
... Tracer studies have
indicated significant absorption of EDTA, Zn-EDTA,
and Ca-EDTA
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Modern Trends in the Treatment of Lead Poisoning
... use of edathamil calcium
disodium (monocalcium disodium
ethylenediaminetetraacetate;
also called calcium EDTA ... .form of
an oral tablet, was first suggested by ...
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Elevated Lead Burden in Chinese Patients without
Occupational ...
... Nevertheless, the EDTA
mobilization test identified 2 patients with occult
plumbism
in this ... webmaster for this BOOK, as well
as for another web site about ORAL ...
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Definitions
... ..48... ..49... ..50...
Menu Position #50. ... Karl Loren is the
author and webmaster
for this BOOK, as well as for another web site about
ORAL CHELATION. ...
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The relationship between iron and lead Absorption in
humans
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Cysteine & Metals or Toxic Metals
... and oral
administration. Author Margel S Address Source J Med
Chem, 1981 Oct, 24:10,
1263-6 Abstract The chelating drugs BAL
(2,3-dimercaptopropanol), EDTA ( ...
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TREATMENT OF LEAD POISONING BY CHELATION
... Belknap, EL: EDTA
in Treatment of Lead Poisoning, Indust. Med. 21:305,
1952. ... Soc.
Exper. Biol. & Med. 74:415, 1950. [_private/navbarbook.htm]
...
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Toxic Metals -- Lead Levels
... dL are detrimental to
cognitive development, (2) EDTA provocation
testing may result
in potentially harmful shifts in the body lead
burden, and (3) oral agents ...
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Cholesterol Studies From 1985 to 1987
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... The oral
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Resume
... Exclusive interview with
Dr. Garry Gordon, "Oral Chelation for Improved
Heart Function"
Life Enhancement" Issue 32, April, 1997. Gordon, G.
and Vance, R., "EDTA ...
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Free Radicals & Toxic Metals
... reserved. ...
published. Karl Loren is the author and webmaster for
this
BOOK, as well as for another web site about ORAL
CHELATION. ...
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COUNCIL ON INDUSTRIAL HEALTH AND COUNCIL ON PHARMACY
AND ...
... of a satisfactory compound
of edathamil (Calcium Disodium Versenate,
ethylenediaminetetraacetic
acid, EDTA ... this BOOK, as well as
for another web site about ORAL ...
www.oralchelation.net/data/EDTA/data14ac.htm
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n-Acetylcysteine & Metals
... formulations. This may
facilitate more convenient oral mesna dosing
in
protocols using high-dose cyclophosphamide or
ifosfamide. ... reserved. ...
www.oralchelation.net/data/ToxicMetals/data13f.htm
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AcetylAid
... folic acid. ...
published. Karl Loren is the author and webmaster for
this
BOOK, as well as for another web site about ORAL
CHELATION. He ...
www.oralchelation.net/data/EDTA/data14x.htm
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Degradation Of Vitamin C
... Dialysis of EDTA-treated
genomic DNA purified by standard proteinase K
digestion/phenol ... 13.2+/-1.7%
versus 8.2+/-1.0%; P<.01) and after 4 weeks of
oral therapy ...
www.oralchelation.net/data/EDTA/data14f.htm
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DANGER UNLOCKED
... [_private/navbarbook.htm]
... Karl Loren is the author and webmaster for
this BOOK, as well as for another web site about
ORAL CHELATION. ...
www.oralchelation.net/data/EDTA/data14an.htm
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The OILING of AMERICA
... and JP Frackelton, "Free
Radical Pathology in Age-Associated Diseases:
Treatment
with EDTA ... webmaster for this BOOK,
as well as for another web site about ORAL
...
www.oralchelation.net/heartdisease/
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Toxic Metals
... and safety, and
establishes it as the premier metal chelation
compound, based on
oral ... The addition of other metals,
eg Zn2+, and metal chelators, eg EDTA, can
...
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