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Multiple System Atrophy -- Another Hopeless Disease

Hopeless diseases are often widely promoted on the web, as being hopeless.  I never agree with such assessments.

Information on this and other pages may have been copied from other sources.  The assertion is made, here, that the use of this information does not not constituted violation of the laws of copyright, in part because of the doctrine of fair comment, about a public entity or person and by a investigative researcher and author.  This page presents information about MSA. This page, and other pages referring to it, comment fairly about MSA as a hopeless disease. I do not agree.  That is the opinion of Karl Loren, voiced in these pages.

Source

Multiple System Atrophy

What is multiple system atrophy?
Multiple system atrophy (MSA) is a neurodegenerative disease marked by a combination of symptoms affecting movement, blood pressure, and other body functions; hence the label "multiple system" atrophy. The cause of MSA is unknown.

What are the various forms of MSA?
Symptoms of MSA vary in distribution, onset and severity from person to person. Because of this, three different diseases were initially described to encompass this range of symptoms: Shy-Drager syndrome, striatonigral degeneration, and olivopontocerebellar atrophy.

In Shy-Drager syndrome, the most prominent symptoms are those involving the autonomic system, the body system that regulates blood pressure, urinary function, and other functions not involving conscious control. Striatonigral degeneration causes parkinsonian symptoms such as slowed movements and rigidity, while olivopontocerebellar atrophy principally affects balance, coordination, and speech.

These diseases are now considered forms of MSA.

What are the symptoms of MSA?
MSA can cause a wide range of symptoms, including:

 

What are the complications of MSA?
MSA progresses over the course of several years to cause more widespread and severe symptoms. Orthostatic hypotension can cause fainting and falls. Loss of coordination, slowed movements, and rigidity can interfere with activities of daily living. Some patients with MSA have mild loss of cognitive abilities, with impairments in attention and speed of thinking.

Are there any treatments for MSA?
A number of drugs can be used to treat the various symptoms of MSA, although they become less effective as the disease progresses.

 

Additional Resources


These review articles provide information directed to medical professionals. The journals and textbooks in which they appear can usually be found in a medical library. Unfortunately, WE MOVE cannot provide copies of these articles.

  1. 1.Wenning GK, Quinn NP. Multiple system atrophy. In: Quinn NP, ed. Parkinsonism. Baillieres Clin Neurol. 1997;6(1):187-204 Abstract
  2. Shulman LS, Weiner, WJ. Multiple system atrophy. In: Watts RL, Koller WC, eds. Movement Disorders: Neurological Principles and Practice. New York, NY: McGraw-Hill; 1997:297-306

All contents Copyright © WE MOVE 2002.   Last Update: June 14, 2002

WE MOVE makes every effort to present medical information that is up-to-date and accurate. The material provided has undergone rigorous medical review. Information regarding the authors, editors, publisher, and medical reviewers of this material of the WE MOVE Web site is listed below.

Medical science is constantly changing. Therefore, the authors, editors, and publisher do not warrant that the information in this text is complete, nor are they responsible for omissions or errors in the text or for the results of the use of this information. This information does not replace consultation with a physician. All medical procedures, drug doses, indications, and contraindications should be discussed with your personal physician.

Medical Editor: Richard Robinson
Medical Review: Horacio Kaufmann, MD; Niall Quinn, MD

 


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