The National Cholesterol
Education Program is based on the
assumption that it is possible to prevent
cardiovascular death in a large number of
people. The expert panel´s main argument
for the new guidelines is that twenty
percent of patients with coronary heart
disease have a new heart attack after ten
years.1
To reach that number
any minor symptom without clinical
significance has been included. Most people
survive even a major heart attack, many
with few or no symptoms after recovery.
What matters is how many die and
this is much
less than twenty percent. No
doubt, the statins lower the risk of dying
from a heart attack, at least in patients
who already have had one,
but the size
of the effect is unimpressive.
In the CARE trial for
instance, the odds of escaping death from a
heart attack in five years for a patient
with manifest heart disease was
94.3%,
which improved to
95.4%
with statin treatment.2 For healthy people
with high cholesterol the effect is even
smaller. In the WOSCOPS trial, the figures
were
98.4% and
98.8%,
respectively.2
These figures do not take into account possible side effects of the treatment.
In most animal
experiments the statins, as well as most
other cholesterol-lowering drugs, produced
cancer,
and they may do it in human beings also.2
In The CARE Trial
Breast Cancer Was Seen Significantly More
Often In The Treatment Group.
In the EXCEL trial
the increase of total mortality in the
treatment group after just one year was
borderline significant.3 Unfortunately the
trial was stopped before further
observations could be made.
The original 1961 advice from the American Heart Association to eat as much polyunsaturated fat as possible has been reduced successively to the present "up to ten per cent".
A commonly prescribed drug for lowering blood cholesterol may affect people's ability to drive or perform other everyday tasks. Lovastatin, sold by Merck and Co. under the name Mevacor and also as mevinolin, could affect attention and reaction speed. Researchers at the University of Pittsburgh told at a meeting of the American Heart Association (AHA) in Orlando, Florida, on November 11 that patients whose cholesterol had been lowered with Lovastatin paid less attention and had delayed psychomotor reflexes.
The researchers said patients who had been given Lovastatin showed decreased attention and psychomotor speed, compared with those who had not received the drug. Those who had the greatest decreases in cholesterol levels suffered the greatest impairment.
But why this limit?
Ten years ago the
main author of the new guidelines stated
that "intakes above 7% of total calories
seemingly cannot be advocated with
prudence" because, as he argued, an excess
of polyunsaturated fat may be carcinogenic
in human beings, just as they are in
experimental animals.2 4
Besides, the benefits
of manipulating dietary fats have never
been proved.2 Instead of preventing
cardiovascular disease the new guidelines
may transform healthy individuals into
unhappy hypochondriacs obsessed with the
chemical composition of their food and
their blood, undermine the art of cuisine,
destroy the joy of eating, and divert
health care money from the sick and the
poor to the rich and the healthy.
References:
1. Expert
Panel on Detection, Evaluation, and
Treatment of High Blood Cholesterol in
Adults. Executive Summary of the Third
Report of the National Cholesterol
Education Program (NCEP) Expert Panel on
Detection, Evaluation, and Treatment of
High Blood Cholesterol in Adults (Adult
Treatment Panel III) JAMA 2001; 285:
2486-2496.
2.
Ravnskov U. The Cholesterol Myths. New
Trends publishing, Washington DC 2000.
3.
Bradford R H, Shear C L, Chremos A N,
Dujovne C A, Franklin F A, Grillo R B,
Higgins J, Langendorfer A, Nash D T, Pool J
L, Schnaper H. Expanded clinical evaluation
of lovastatin (EXCEL) study results. Arch
Intern Med 1991; 151: 43-49.
4. Grundy SM. George Lyman Duff Memorial Lecture. Multifactorial etiology of hypercholesterolemia. Implications for prevention of coronary heart disease.
Arteriosclerosis 1991; 11: 1619-1635.
British Medical Journal May 28, 2001
For more information, see Dr. Ravnskov's website at http://www.ravnskov.nu/cholesterol.htm.
If you would like to purchase his book The Cholesterol Myths on Amazon.com, then CLICK HERE.
DR. MERCOLA'S COMMENT:
Thanks to Dr. Stephen Byrnes for posting this in his newsletter.
This is an excellent follow-up to an article that was posted in May and it provides some new data to the table on the relative benefits of statin drugs and the side effects of an increase in cancer.
I will also repost
my comment from that article for those that
missed it:
OK, here we go
again. Now the "experts" have raised the
ante. They changed the "normal" range so
even more people will be put on cholesterol
lowering drugs.
Prior to the new
recommendations 13 million Americans
"qualified" to be placed on these drugs.
With these new recommendations 36 million
Americans now qualify--nearly triple the
amount.
After all, that is the answer, isn't it? If people can't lower their cholesterol by following the low-fat nonsense then they need to take these drugs to prevent them from falling prey to the number one killer in the US, heart disease.
Hogwash. Nothing
could be further from the truth.
If you have been
receiving the newsletter for some time you
will be familiar with my position on this
issue. If not, I would encourage you to
study the links below.
About one year
ago, the experts predicted that
HALF the population will be taking these
types of drugs.
The big issue here
is that these potent medications may be
available over the counter in the near
future with a massive PR campaign to
encourage people to swallow these
potentially dangerous drugs.
The amazing thing
about these new recommendations is that
they completely ignore the previously
published evidence that are quite clear in
documenting that the actual cholesterol
level itself is not the most important risk
factor. It is actually the ratio between
the level of total cholesterol and HDL
cholesterol.
The ideal
HDL/cholesterol ratio should be higher than
25% and generally speaking the higher the
better.
The ideal
triglyceride/HDL ratio should be below 2.0.
If you did not
know any better and just listened to the
"experts" you would think cholesterol is an
evil substance and that most of us would
benefit from lowering our cholesterol as
low as possible.
Not so.
Cholesterol is a vitally important
substance that is responsible for building
our cell membranes and many of our
hormones. If the level drops to low we are
actually at increased risk for depression.
There are likely
to be some people who benefit from them,
but it is probably far less than 5% of the
people who currently take them. These are
individuals with total cholesterol above
350 who have inherited liver processing
problems.
If these
individuals take the statin drugs however,
they should also take Coenzyme Q10, which
is important for heart health and, like
cholesterol, is reduced when one takes
these drugs. The proper way for nearly
everyone else to control their cholesterol
levels is by reducing their grain intake by
following the food choice program I
recommend.
Another problem is
the fact that low cholesterol is associated
with numerous problems, as you can see from
some of the studies below.
Related Articles:
Cholesterol Drugs: How Expensive Is Too Expensive?
Cholesterol Lowering Drugs Suppress Immune System
Low Cholesterol Causes Aggressive Behavior
Low Cholesterol Linked to Stroke Risk
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