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Jiang He -- Author Of Report On Chinese Heart Disease Epidemic

Source

[Karl Note:  Here is an excellent example of how a young man, studying first in China, then in the US, can get himself on the fast track to success and high recognition.  All he has to do is figure out what some drug company, preferably one of the large ones, wants out of "research findings," and then deliver that.  It is even possible that most of his scientific reports are honest, but here is someone who has sold his soul to the devil, in the current case, Pfizer, going to China on their nickel to get the research results that THEY wanted.  And so does Tulane University serve the public trust!]

 

Jiang He

Dr. He is an associate professor in the Department of Epidemiology at the Tulane University School of Public Health and Tropical Medicine. Dr. He received his medical degree and completed his residency in internal medicine at the Jiangxi Medical College, the People's Republic of China. He then went to the Peking Union Medical College and Chinese Academy of Medical Sciences to study a doctor of medical science degree in epidemiology. Dr. He came to US in 1989 and completed his PhD and postdoctoral training in the Department of Epidemiology at the Johns Hopkins School of Hygiene and Public Health.

In 1996, Dr. He became a core faculty member at the Welch Center for Prevention, Epidemiology, and Clinical Research and an instructor in the Department of Epidemiology, the Johns Hopkins University School of Hygiene and Public Health. In 1997, Dr. He joined the faculty of the Department of Biostatistics and Epidemiology at the Tulane University School of Public Health and Tropical Medicine as an assistant professor. In 2000, he was promoted to associate professor with tenure.

Dr. He has been twice nominated as finalist for the Jeremiah Stamler Research Award for New Investigators by the American Heart Association, Council on Epidemiology and Prevention. Dr. He received the "People to Watch" award from New Orleans Magazine in 1999 and the Tulane University President’s Award for Excellence in Research in 2000.

Dr. He's research has been focus on the etiology and prevention of cardiovascular disease, including hypertension, diabetes, dyslipidemia, coronary heart disease, stroke, congestive heart failure, and end-stage renal disease. Dr. He has been Principal Investigators for several research projects sponsored by the National Institutes of Health and American Heart Association. He has published more than 60 scientific research papers.

Research Interests

Selected Publications


General Clinical Research Center

Tulane - Charity Hospital - LSU

Source

[Karl Note:  Here is a research study PROPOSAL showing that Dr. Jiang appears to be investigating whether so-called "alternative" methods of lowering blood pressure will work.  This study cannot show anything but a negative result -- otherwise Dr. Jiang would not be promoted. But, now that he has this study under his belt, he looks "balanced" when it comes to studying DRUGS to accomplish the same thing!  Thus the evil starts very early in some researcher's life, and even HE may think he is pursuing some noble cause!]

 

 
INSTITUTION & LOCATION
DEGREE
YEAR(S)
FIELD OF STUDY
  Jiangxi Medical College - Jiangxi, PR China
MD
1982
Medicine
   
  Peking Union Medical College - Beijing, PR China
DMedSc
1994
Epidemiology
   
  Johns Hopkins University School of Hygiene and Public Health - Baltimore, MA
PhD
1996
Epidemiology

Protocol(s):

Randomized Controlled Trial of Dietary Fiber and Blood Pressure (97-0037).
  SPECIFIC AIMS
The primary aims of the proposed trial are to test whether, over 6 months of supplementation, 10 grams of soluble fiber ( -glucan extracted from oat bran) a day will decrease systolic (SBP) and diastolic (DBP) blood pressure in 200 participants with untreated high normal BP (SBP: 130 to 139 mm Hg; or DBP: 80 to 89 mm Hg). The proposed trial is designed to provide greater than 80% statistical power to detect a 3.0 mm Hg reduction in SBP and a 2.0 mm Hg reduction in DBP at a significance level of 0.05 using a two-tailed test. Additional aims are to test whether dietary fiber supplementation will reduce:
-Serum glucose and insulin levels;
-Serum total- and LDL-cholesterol, and triglyceride levels;
-Body weight.
The impact of change in serum levels of insulin, glucose and lipids, and body weight on the possible reduction in BP will be explored. The proposed trial will provide insight into the mechanisms of the BP-lowering effect of dietary fiber.
   

Source

[Karl Note:  See the plan developing.  Here in 1996 Dr. Jiang is establishing the politically correct data, based on "independent research" that when rural Chinese move to the big city, where they eat the foods condemned by the American Heart Association, they get high cholesterol.  This man has planned well his success in academia -- the drug companies have followed his career with great interest, guiding a bit, here and there, as necessary. As long as he stays on THEIR path, he will succeed.]

 

 

On Research:
Paying For The
Sins Of The City

Health: Risk factors
climb for a rural
Chinese people in cities.

Randolph Fillmore
School of Public Health

Isolated in rural China, the ethnic Yi don't suffer from cardiovascular diseases. But when they move to the city, leaving their traditional life styles and diets at home in exchange for life in the faster lane where higher fat diets and less physical activity are the rule, they often develop higher blood pressure and hypertension and may become overweight.

According to School of Public Health researcher Jiang He, these conclusions from a two-year study of Yi farmers and migrants have implications for making life-style dietary changes to lowering cardiovascular disease risks.

The study was jointly conducted by researchers from the Welch Center for Prevention, Epidemiology and Clinical Research at the School of Public Health and researchers in the People's Republic of China.

The study, which will appear in the Nov. 1 issue of the American Journal of Epidemiology, suggests that diets higher in fat that increase serum lipid levels--high cholesterol--when coupled with less physical activity, are leading the urban Yi not only down the path toward greater sophistication, but to cardiovascular diseases as well.

"In the 1950s, Yi farmers, who live on potatoes, rice, corn, oats and buckwheat, began to migrate to Xichang City," Jiang He said. "At home, the Yi only eat meat for celebrations, for weddings and funerals. Animal and vegetable fat are not used for cooking."

With an early interest in the health and diet of remote peoples, Jiang He began his research on the Yi when studying at Peking Union Medical College with Guan-Qing He, a co-researcher in this study and a 1940s alumnus of the School of Public Health. After coming to the school, Jiang He went back to the isolated Yi villages, 3,000 meters above sea level, to gather more data before making the connection to urban, migrant Yi.

Backpacking into the mountainous villages, Jiang He took blood pressures and drew blood to measure serum total and high density lipoprotein cholesterol and serum triglyceride levels. After testing more than 500 Yi farmers with the help of local physicians, similar tests were conducted with 300 migrants in their new urban setting. The data on the urban Yi, of Mongolian descent, were then compared with ethnic Han peoples, non-Mongolians who are the most prominent ethnic group in China and live in the same city. Information on age, cigarette smoking, alcohol consumption, nutrition and physical activity was obtained by questionnaire. Across the board, Yi migrants had higher blood pressure, higher cholesterol and engaged in less physical activity than their stay-at-home relatives. As a result, their cholesterol and other health profiles were much more like those of their new urban neighbors, the Han. According to Jiang He, the data tend to dispel the notion of a strong genetic link to higher cholesterol in favor of an environmental, life-style correlation.

"This study gave us an unusual opportunity to compare the effects of environment and ethnic heritage on serum lipid levels," said Jiang He. "Most people talk about high cholesterol as a genetic problem, running in families. This study confirmed that dietary fat and cholesterol intake--life-style eating patterns--are important in high cholesterol. The diets of the migrants were higher in fats and lower in fiber. Their cigarette smoking, alcohol consumption and lack of physical activity suggests that their new life-styles can lead to hyperlipidemia and cardiovascular diseases."

Looking at the data on cardiovascular risk and serum cholesterol levels, the cholesterol-related life-style changes put the Yi migrants at a 76 percent greater chance of developing cardiovascular illness than their relatives at home, according to Michael J. Klag, also of The Welsh Center and co-author of the study. In earlier studies, Jiang He and Klag looked at the oat and buckwheat diet of the rural Yi and found that their diet correlated with their low prevalence of cardiovascular diseases.

"Because oats and buckwheat are associated with low serum cholesterol, these foods may be useful in life-style modifications to reduce or prevent cardiovascular diseases," said Jiang He. "The lives of the rural Yi are changing because they are more in touch with the urban areas. I would like to go back to see how changes are affecting their diet and health," Jiang He added.

 


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[Karl Note: When a young professor gets something published in JAMA, you know he is on his way!  Unfortunately he is on the wrong way!]


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Dietary Sodium Intake and Subsequent Risk of Cardiovascular Disease in Overweight Adults  
 
 
Author Information  Jiang He, MD, PhD; Lorraine G. Ogden, MS; Suma Vupputuri, MPH; Lydia A. Bazzano, BS; Catherine Loria, PhD, MS; Paul K. Whelton, MD, MSc

 

Context  Dietary sodium is positively associated with blood pressure, and ecological and animal studies both have suggested that high dietary sodium intake increases stroke mortality.

Objective  To examine the risk of cardiovascular disease associated with dietary sodium intake in overweight and nonoverweight persons.

Design  Prospective cohort study.

Setting  The first National Health and Nutrition Examination Survey Epidemiologic Follow-up Study, conducted in 1982-1984, 1986, 1987, and 1992.

Participants  Of those aged 25 to 74 years when the survey was conducted in 1971-1975 (14,407 participants), a total of 2688 overweight and 6797 nonoverweight persons were included in the analysis.

Main Outcome Measures  Dietary sodium and energy intake were estimated at baseline using a single 24-hour dietary recall method. Incidence and mortality data for cardiovascular disease were obtained from medical records and death certificates.

Results  For overweight and nonoverweight persons, over an average of 19 years of follow-up, the total number of documented cases were as follows: 680 stroke events (210 fatal), 1727 coronary heart disease events (614 fatal), 895 cardiovascular disease deaths, and 2486 deaths from all causes. Among overweight persons with an average energy intake of 7452 kJ, a 100 mmol higher sodium intake was associated with a 32% increase (relative risk [RR], 1.32; 95% confidence interval [CI], 1.07-1.64; P = .01) in stroke incidence, 89% increase (RR, 1.89; 95% CI, 1.31-2.74; P<.001) in stroke mortality, 44% increase (RR, 1.44; 95% CI, 1.14-1.81; P = .002) in coronary heart disease mortality, 61% increase (RR, 1.61; 95% CI, 1.32-1.96; P<.001) in cardiovascular disease mortality, and 39% increase (RR, 1.39; 95% CI, 1.23-1.58; P<.001) in mortality from all causes. Dietary sodium intake was not significantly associated with cardiovascular disease risk in nonoverweight persons.

Conclusions  Our analysis indicates that high sodium intake is strongly and independently associated with an increased risk of cardiovascular disease and all-cause mortality in overweight persons.

[Karl Note:  I would not disagree with this finding, sodium is generally the substance you get when you drink sodas, and they are the bane of the American diet.  Dr. Jiang is publishing the stuff that will make him seem one of the good guys, but it has been well known for years that soda was a bad item in your diet.  No, the real reason for this research is to make Dr. Jiang appear to be one of the good guys.  When you get down to the bottom line, the drug companies know that people will continue to drink soft drinks, with lots of sodium, and whether THAT has anything to do with heart disease or not is beside the point.  The real point is that people will need the cholesterol-lowering drugs that are coming along on Dr. Jiang's future research path -- this article was published in 1999.  It was in April 2002 that Dr. Jiang finally got into the main track of supporting the drug companies -- his "alternative health" credentials having been established.  Click here for the April 2002 study results -- Dr. Jiang is now ready to support Lipitor and other such drugs -- directly!]

JAMA. 1999;282:2027-2034

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Author/Article Information

 
 
Author Affiliations: Departments of Epidemiology (Drs He and Whelton and Mss Vupputuri and Bazzano), and Biostatistics (Ms Ogden), Tulane University School of Public Health and Tropical Medicine, New Orleans, La; and the National Center for Health Statistics, Hyattsville, Md (Dr Loria).
 
Corresponding Author and Reprints: Jiang He, MD, PhD, Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, 1430 Tulane Ave SL18, New Orleans, LA 70112 (e-mail: jhe@mailhost.tcs.tulane.edu).

Funding/Support: This study was supported by grant R03 HL61954, and in part by grant R01 HL60300 from the National Heart, Lung, and Blood Institute and a career development grant to Dr He from the Office of the Dean, Tulane University School of Public Health and Tropical Medicine. The NHANES I Epidemiologic Follow-up Study has been developed and funded by the National Center for Health Statistics; National Institute on Aging; National Cancer Institute; National Institute of Child Health and Human Development; National Heart, Lung, and Blood Institute; National Institute of Mental Health; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Allergy and Infectious Diseases; National Institute of Neurological and Communicative Disorders and Stroke; Centers for Disease Control and Prevention; and US Department of Agriculture.




 


 
 
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